PKPD Principles

Objectives:

  1. Define pharmacokinetics and pharmacodynamics in the context of antiinfective therapy

  2. Explain the key pharmacokinetic parameters (ADME) and their clinical relevance

  3. Identify the three primary PK-PD indices and their associated antibiotic classes

  4. Compare concentration-dependent vs. time-dependent killing patterns

  5. Apply extended-interval and continuous infusion dosing strategies

  6. Discuss therapeutic drug monitoring principles for antiinfectives

  7. Apply PK-PD concepts to clinical case scenarios


Lecture video

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Lecture transcript:

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